Neville N. Osborne's Biochemistry of Characterised Neurons PDF

By Neville N. Osborne

ISBN-10: 0080215033

ISBN-13: 9780080215037

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Extra resources for Biochemistry of Characterised Neurons

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5 pmol of 5-HT/ cell body and confirm their conclusion that approximately 40% of the 5-HT in a ganglion is in its two Retzius cell bodies. 1 pmol/cell body) obtained from the analyses of individual cells is similar to that obtained by Rude et al. 6 pmol/cell body) on pooled samples of 35-49 cells each. Approximately 25 nmol 5-HT/g wet weight was found in the vasofibrous tissue that surrounds the blood sinus containing the leech central nervous system (Table 2 ) . Chromaffin cells in the vasofibrous tissue, which became intensely labeled following H-5-HT injection into the leech, have been described (Coggeshall & Yaksta-Sauerland, 1974).

Physiol. 18, 687-690. A. J. (1967). The action of acetylcholine, dopamine and 5-hydroxytryptamine on the spontaneous activity of, the cells of Retzius of the leech, Hirudo medicinalis. Brit. J. Pharmac. and Chemotherap. 30, 644-654. Koidl,: B. (1974). The GABA content of the central nervous system of Crustacea,and annelida: a comparison. J. Comp. Physiol. 94, 49-55. H. R. (1973). Analysis of pineal and brain indolealkylamines by gas chromatography-mass spectrometry. Adv. Biochem. Psychopharm. 7, 33-43.

The radioactivity in the Retzius cells 3 3 following the injection of both H-5-HT and H-5-HTP was predominatly in 5-HT. The Retzius cells examined by autoradio- graphy were intensely and specifically labeled following Fig. 1. A photomicrograph of the ventral surface of a leech segmental ganglion. The connectives to adjacent ganglia run toward the top and bottom of the picture, and the lateral roots to the right and left. The Retzius cells are the two large cells just below the center of the picture.

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Biochemistry of Characterised Neurons by Neville N. Osborne


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